PYRTPlan Your Road Trips
Create TripCommunityMerchandise
PYRTPlan Your Road Trips
Create TripCommunityMerchandise
A picturesque hilltop town in Italy surrounded by lush green fields and vibrant landscapes.
Aerial view of Costigliole d'Asti shrouded in early morning fog, Piemonte, Italy.
Picturesque landscape of vineyards and village in Belvedere Langhe, Piemonte, Italy.
Photo by William Giustozzi on Pexels
Destinations
Home›Destinations›Sansepolcro
EuropeItalyTuscany

Sansepolcro

Tuscany, Italy · Europe

About Sansepolcro

Sansepolcro sits on the route: 10 minutes from San Giustino, 40km from San Leo.

Sansepolcro is in Tuscany, Italy, with about 12,000 people. You drive on the right here. The nearest town is San Giustino, about 4 km away.

Sansepolcro, formerly Borgo Santo Sepolcro, is a town and comune founded in the 11th century, located in the Italian Province of Arezzo in the eastern part of the region of Tuscany. Situated on the upper reaches of the Tiber river, the town is the birthplace of the painters Piero della Francesca, Raffaellino del Colle

Read more (a pupil of Raphael), Matteo di Giovanni, Santi di Tito, and Angiolo Tricca. It was also the birthplace of the Italian mathematician Luca Pacioli, and of Matteo Cioni, who translated Piero della Francesca's treatise about perspective in painting (De prospectiva pingendi) into Latin. Today, the economy of the town is based on agriculture, industrial manufacturing, food processing and pharmaceuticals. It is the home of Buitoni pasta, founded by Giulia Buitoni in 1827.

Read more on Wikipedia

Where to Stay in Sansepolcro

Compare prices across Booking.com, Airbnb, Expedia, and more. Select your dates to see availability.

Filter presets

Pick your must-haves once: provider links open pre-filtered. Each filter lists which sites it applies to.

Booking.comExpediaTripAdvisorHotels.comAgodaAirbnb

Compare before you book!

Prices can vary significantly between platforms. We recommend checking at least 2-3 sites to find the best deal for your stay in Sansepolcro.

Explore the Area

Discover famous landmarks, scenic roads, and more near Sansepolcro.

Loading map...
Open in Google Maps

Frequently Asked Questions

What is there to see near Sansepolcro?

Within an hour or so of Sansepolcro: San Leo (40 km), Urbino (44 km), Historic Centre of San Marino (47 km), Montepulciano (60 km).

Are there any good drives near Sansepolcro?

The nearest famous roads are Strada Chiantigiana (SR222), Autostrada del Sole and Passo della Futa.

Where is Sansepolcro?

Sansepolcro is in Tuscany, Italy, about 4 km from San Giustino.

Road trip

Drive to Sansepolcro

Add it as a stop and the planner works out the driving, the nights and what's worth seeing on the way.

Start planning

What's nearby?

Swipe through places to go

Places within a drive of Sansepolcro. Keep the ones you like and add them to your trip.

Explore now

Quick Information

Population
12,364
Continent
Europe
Country
Italy
Region
Tuscany
Timezone
Europe/Rome
Coordinates
43.5726, 12.1386

Emergency & Services

Essential numbers in Italy

Police
113
Ambulance
118
Fire
115
All emergencies
112
Driving side
right

ACI roadside assistance: 803 116. ZTL (limited traffic zones) in city centres are camera-enforced.

Full driving guide for Italy

Tags

EuropeItalyTuscanyTown

Worth the detour from Sansepolcro

4 notable places within an hour's drive.

castle

San Leo

Fortress town on a sheer limestone crag in the Montefeltro, where the Renaissance rocca, prison of the alchemist Cagliostro: seems to grow from the rock itself. The single road in climbs through a cleft in the cliff.

40 km · about 45 min drive

landmark

Urbino

Walled Renaissance city rising in brick tiers over the Marche hills, birthplace of Raphael and seat of Federico da Montefeltro's Palazzo Ducale: now home to Piero della Francesca's Flagellation. A UNESCO site most itineraries inexplicably skip.

44 km · about 50 min drive

landmark

Historic Centre of San Marino

UNESCO-listed micro-state capital atop Mount Titano with three iconic medieval towers and panoramic views to the Adriatic.

47 km · about 55 min drive

landmark

Montepulciano

A Renaissance hilltop town in southern Tuscany celebrated for its Vino Nobile wine and elegant Piazza Grande.

60 km · about 70 min drive

Driving roads near Sansepolcro

  • 66 kmStrada Chiantigiana (SR222)The classic Chianti wine road winds between Florence and Siena past vineyards, castles and cypress-lined ridges.
  • 73 kmPiazzale MichelangeloA panoramic terrace above Florence offering the most iconic sweeping view of the city's skyline with the Duomo and Ponte Vecchio.
  • 74 kmAutostrada del SoleItaly's original motorway running from Milan to Naples through Tuscany and past Rome, an icon of postwar Italian engineering.
  • 74 kmVal d'OrciaA UNESCO-listed Tuscan valley of rolling hills, cypress-lined roads, and golden wheat fields that define the Italian countryside.

Driving in Italy

Drives on
the right
Petrol
~€1.82/litre
Motorway tolls
~€8.50/100km

When to drive here

April to October

Nearby Destinations

Other places to explore near Sansepolcro.

Anghiari

🇮🇹 Italy

7 km awayPop. 2,784

Selci-Lama

🇮🇹 Italy

9 km awayPop. 4,837

Città di Castello

🇮🇹 Italy

14 km awayPop. 22,497

Arezzo

🇮🇹 Italy

24 km awayPop. 100,734

Montone

🇮🇹 Italy

28 km awayPop. 567

Plan a trip around Sansepolcro

Italy road trip planner

Your trip starts here

Plan a road trip from Sansepolcro.

Pick the days, drop in the stops, and share it with whoever's coming.

Start planning
PYRT

The ultimate road trip planning platform. Discover 150,000+ destinations worldwide, plan scenic routes, and create unforgettable adventures.

Inspiration

  • Discover Trips
  • Travel Guides
  • Community

The Product

  • Calendar Planner
  • Integrations
  • How It Works
  • Collaboration Mode
  • Get the App
  • Merchandise: PYRT Supply Co.
  • Become a Creator
  • Trip Marketplace

Plan Your Trip

  • Road Trip Planner
  • Famous Routes
  • Drive Times & Distances
  • Planners by Country
  • Best Road Trip Planner App
  • Discover Road Trips
  • Events
  • Travel Guides
  • How It Works
  • My Trips
  • Community Groups

Company

  • Terms of Service
  • Privacy Policy
  • About PYRT
  • Support
  • Contact Us
  • Sign In
  • Create Account

© 2026 Plan Your Road Trips. All rights reserved.

•[email protected]
Data sources:GeoNames (CC BY 4.0)•Wikimedia Commons (CC BY-SA)•Mapbox•Photography: George Lawrence