Cathedrals & Temples
Florence Cathedral (Cattedrale di Santa Maria del Fiore)
Brunelleschi's magnificent terracotta dome dominates the Florence skyline and remains the largest brick dome ever constructed.
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Road trip route · Italy
Rome to Pisa drive time, distance, costs & the best stops
- Drive time
- 4 hr 3 min
- Distance
- 372 km
- Fuel (est.)
- €48
- Tolls (est.)
- €21
The Rome to Pisa drive
The drive from Rome to Pisa covers 231 miles (372 km) and takes about 4 hr 3 min without stops. That makes it a comfortable one-day drive. Leave in the morning and you'll arrive with the day ahead of you.
Expect fuel for a typical petrol car (~40 mpg) to cost around €48 one-way plus roughly €21 in motorway tolls. Prices shift monthly, so treat these as ballpark figures.
At 231 miles this is longer than 66% of the 144 routes covered here.
Best stops between Rome and Pisa
Within ~30 km of the driving route, worth the detour.
Cathedrals & Temples
Orvieto
A dramatic Umbrian hill town perched atop volcanic tufa cliffs, crowned by one of Italy's most ornate Gothic cathedrals.
Historic Highways
Autostrada del Sole
Italy's original motorway running from Milan to Naples through Tuscany and past Rome, an icon of postwar Italian engineering.
Museums
Uffizi Gallery
Italy's foremost art gallery, housing the greatest collection of Renaissance art including Botticelli's Birth of Venus.
Landmarks
Montepulciano
A Renaissance hilltop town in southern Tuscany celebrated for its Vino Nobile wine and elegant Piazza Grande.
Landmarks
Pienza
A tiny Tuscan town redesigned in the 15th century as an ideal Renaissance city and now a UNESCO World Heritage Site.
Landmarks
Villa d'Este (Tivoli)
A Renaissance cardinal's villa near Rome with one of the finest Italian gardens, featuring hundreds of elaborate fountains and water features.
Scenic Viewpoints
Piazzale Michelangelo
A panoramic terrace above Florence offering the most iconic sweeping view of the city's skyline with the Duomo and Ponte Vecchio.
Racetracks
Mugello Circuit
Ferrari-owned circuit in a green Tuscan valley, host of the Italian MotoGP. Its 1.1 km start straight and fast sweepers make it one of the most beautiful racetracks in the world.
What you need for this drive
Rules for each country on the route, in the order you meet them.
Italy
- Motorway
- 130 km/h · 50 in town
- Tolls
- Autostrade
- Must carry
- warning triangle, hi-vis vest
- Winter tyres
- 15 November - 15 April
Low-emission zones: ZTL (Zona a Traffico Limitato).
Checked against national road authorities and the ECB reference rates. Rules change — confirm before you travel.
Famous drives in Italy
Legendary routes you could bolt onto this trip, with real distances and stop counts.
Rome to Pisa FAQs
How long is the drive from Rome to Pisa?
Driving from Rome to Pisa takes about 4 hr 3 min nonstop, covering 231 miles (372 km). Add time for breaks: most drivers stop every 2 hours.
How much does it cost to drive from Rome to Pisa?
Fuel for a typical petrol car (~40 mpg) costs roughly €48 one-way. Expect around €21 in motorway tolls. Estimates are indicative: prices change monthly.
Can I drive from Rome to Pisa in one day?
Yes, at about 4 hr 3 min of driving, Rome to Pisa is a comfortable one-day drive with a couple of breaks.
What other drives can I plan on Plan Your Road Trips?
We publish drive times, distances and fuel estimates for 144 routes across Europe and beyond, including 17 other drives in the same country. Browse them all on the routes index.
What are the best stops between Rome and Pisa?
Top-rated stops in the drive corridor include Florence Cathedral (Cattedrale di Santa Maria del Fiore), Orvieto, Autostrada del Sole: see the full list of 9 stops on this page.
More drives from Rome & Pisa
Planning a bigger trip? Try the free Italy road trip planner, browse every destination we cover, take it with you on the road, or read the driving in Italy guide.